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HAS HISTOLOGY OF MALIGNANT BREAST CANCER ANY IMPACT ON SONOGRAPHIC IMAGE CHARACTERISTICS?
Kassim A. H. Taj-Aldean*, Kadhim Ch. Hasan Dept. of Surgery/ College of Medicine /Babylon University, Hilla, Iraq. Dept. of Surgery/ College of Medicine /Babylon University, Hilla, Iraq. Email: kassim33amir@yahoo.com Received on: 10-02-2017 Accepted on: 22-03-2017

Abstract
This study aimed to determine if the histopathological type of malignant breast cancer affects the imaging pattern
when the breast is evaluated by ultrasound. A prospective study of female patients with palpable breast mass (es),
which were suspected to be malignant, was done over nine months period. Those who had palpable suspect masses
were included. They were examined by 2 seniors consultant in radio imaging of more than 5 years’ experience in
breast ultrasound. Tru-cut or Open surgical biopsies and histopathological examinations were done for the lumps of
all the enrolled cases whether radio imaging examinations indicated malignancy or not. Out of 107 cases, 7 were
excluded; 3 were proved benign sonographically and histopathologically, 1 case was recurrent breast cancer,1 case
escaped follow up while 100 were diagnosed histopathologically as malignant breast cancers. Out of the 100
malignant breast cancer cases,16(16%) were misdiagnosed as benign by sonographic evaluation. The false negative
rate was 16%. The histopathological types of cancer cases were 82 (82%) infiltrating ductal carcinomas. Infiltrating
lobular carcinomas 6(6%), medullary carcinomas 4 (4%) mucinous carcinomas 4(4%) and 4(4%) papillary tumors.
All 82 infiltrating ductal carcinomas and 2 out of 4 (50%) papillary tumors were correctly diagnosed. All cases of
Infiltrating lobular carcinomas 6 (6%), medullary carcinomas 4(4%) mucinous carcinomas 4(4%) in addition to 50%
papillary type were misdiagnosed. The study concluded that histology of the tumor has a significant impact on
sonographic presentation of breast cancer. True- cut or open biopsy can solve the problem if the clinical exam
suspects malignancy.