Genus Pseudomonas includes different species, each has the ability to produce different types of
characteristic exopigments with their various manners of activities. This study includes production of
Pseudomonas pigments like Pyocyanin and fluorescin in liquid culture media and used to examine their
antibacterial activity. Also their cytotoxic effects on normal cell (Vero cell line) were used in vitro. The results
revealed that pyocyanin pigment has growth stimulatory effect on vero-cell line caused increase in the growth
of the cells number, especially at a concentration 30-40%, while fluorescin has cytotoxic inhibitory effect on
vero-cell line causing inhibition in growth of the cells number, the inhibition ranged from 55-75%, especially
at a concentration 30-40%. Pseudomonas exopigments are effectual antigrowth agents against different
bacterial isolates, as well as human cells lines.