معلومات البحث الكاملة في مستودع بيانات الجامعة

عنوان البحث(Papers / Research Title)


Assessment of Nephroprotective role of Irbesartan against gentamicin induced nephrotoxicity in rats


الناشر \ المحرر \ الكاتب (Author / Editor / Publisher)

 
فاطمة عدنان علي الزبيدي

Citation Information


فاطمة,عدنان,علي,الزبيدي ,Assessment of Nephroprotective role of Irbesartan against gentamicin induced nephrotoxicity in rats , Time 31/03/2018 20:20:14 : كلية الصيدلة

وصف الابستركت (Abstract)


The present study was undertaken to assess the renoprotective effect of irbesartan on gentamicin induced nephrotoxicity in male rats.

الوصف الكامل (Full Abstract)

Abstract:
Aims of study : The present study was undertaken to assess the renoprotective effect of
irbesartan on gentamicin induced nephrotoxicity in male rats.
Materials and methods: Fifteen male adult Sprague-Dawely rats were enrolled in this
study, rats were separated randomly into 3 groups, five rats in each group, the first group
maintained on normal standard chow diet, served as control group. The second group
received gentamicin 100 mg/kg/day, i.p for 4 weeks. The third group received gentamicin
100mg/kg/day i.p concomitantly with irbesartan 25 mg/kg/day p.o for 4 weeks.
Results: Gentamicin treatment increased serum urea, creatinine and tissue
malondialdehyde (MDA) significantly. Irbesartan treatment decreased serum urea, creatinine
and tissue MDA significantly.
Conclusion: Gentamicin induced nenephrotoxicity can be prevented by coadministration
with irbesartan.

تحميل الملف المرفق Download Attached File

تحميل الملف من سيرفر شبكة جامعة بابل (Paper Link on Network Server) repository publications

البحث في الموقع

Authors, Titles, Abstracts

Full Text




خيارات العرض والخدمات


وصلات مرتبطة بهذا البحث