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عنوان البحث(Papers / Research Title)


Evaluation of Antifungal and Antibacterial Activity and Analysis of Bioactive Phytochemical Compounds of Cinnamomum zeylanicum (Cinnamon bark) using Gas Chromatography-Mass Spectrometry


الناشر \ المحرر \ الكاتب (Author / Editor / Publisher)

 
هدى جاسم محمد التميمي

Citation Information


هدى,جاسم,محمد,التميمي ,Evaluation of Antifungal and Antibacterial Activity and Analysis of Bioactive Phytochemical Compounds of Cinnamomum zeylanicum (Cinnamon bark) using Gas Chromatography-Mass Spectrometry , Time 13/11/2016 09:21:33 : كلية العلوم للبنات

وصف الابستركت (Abstract)


Thirty nine bioactive phytochemical compounds were identified in the methanolic extract of Cinnamon bark.

الوصف الكامل (Full Abstract)

Phytochemicals are chemical compounds often referred to as secondary metabolites. Thirty
nine bioactive phytochemical compounds were identified in the methanolic extract of Cinnamon
bark. The identification of phytochemical compounds is based on the peak area, retention
time molecular weight and molecular formula. GC-MS analysis of Cinnamomum zeylanicum
revealed the existence of the 6 -Oxa-bicyclo[3.1.0]hexan-3-one, Benzaldehyde, Cyclohexene,4-
isopropenyl-1-methoxymethoxymethyl, Benzoic acid- methyl ester, Benzaldehyde dimethyl
acetal, Benzenepropanal, Benzylidenemalonaldehyde, 3-Phenylpropanol, Cinnamaldehyde, (E),
2-Propen- 1- ol,3-phenyl, 9-Methoxybicyclo[6.1.0]nona – 2,4,6- triene , 1,3-Bis(cinnamoyloxymethyl)
adamantine, Alfa.– Copaene, Naphthalene , 1,2,3,5,6,7,8,8a-octahydro-1,8a-dimethyl-7-(1-methyl),
Cis – 2-Methoxycinnamic acid, Bicyclo[3.1.1]hept-2-ene,2,6- dimethyl-6-(4-methyl-3-pentenyl),
Trans-2-Hydroxycinnamic acid , methyl ester, y-Muurolene, ?-Guaiene, Cadala-1(10),3,8-triene,
Isolongifolene,4,5,9,10-dehydro, Cubenol, Tau-Muurolol, ?-Cadinol , Spiro[tricyclo[4.4.0.0(5.9)]
decane-10.2oxirane],1-methyl-4-isoprol, 6-Isopropenyl-4,8q-dimethyl-1,2,3,5,6,7,8,8aoctahydronaphthalen,
Ethyl9,9-difomylnona-2,4,6,8-tetraenoate, Trans-13-Octadecenoic acid,
Tributyl acetylcitrate, 9,12,15-Octadecatrienoic acid ,2,3-dihydroxypropyl ester, 9-Octadecenamide,
17.alfa.-21?-28,30-Bisnorhopane, 17.alfa.-21?-28,30-Bisnorhopane, Androstan-3-one,cyclic 1,2-
ethanediyl mercaptole , (5?), (4H)4a,5,6,7,8,8a-Hexahydrobenzopyran-5-one-3-carboxamide,2,
4H-Cyclopropa[5´,6´]benz [1´,2´,7,8]azuleno[5,6]oxiren-4-one,8,8a, (22S)-21-Acetoxy-6?,11?dihydroxy-
16?,17?-propylmethylenediox, (+)-?-Tocopherol,O-methyl and Stigmasterol. Cinnamomum
zeylanicum contain chemical constitutions which may be useful for various herbal formulation as
anti-inflammatory, analgesic, antipyretic, cardiac tonic and antiasthamatic. Cinnamomum zeylanicum
was highly active against Aspergillus flavus (6.16±0.42). Methanolic extract of bioactive compounds
of Cinnamomum zeylanicum was assayed for in vitro antibacterial activity against Pseudomonas
aerogenosa, Escherichia coli, Proteus mirabilis, Staphylococcus aureus and Klebsiella pneumonia
by using the diffusion method in agar. The zone of inhibition were compared with different standard
antibiotics. The diameters of inhibition zones ranged from 6.12±0.52 to 0.39±0.17 mm for all
treatments.

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