عنوان البحث(Papers / Research Title)
Bacterial Profile of Blood Stream Infections In Children Less Than Three Years Old
الناشر \ المحرر \ الكاتب (Author / Editor / Publisher)
علاء هاني حسن الجراخ
Citation Information
علاء,هاني,حسن,الجراخ ,Bacterial Profile of Blood Stream Infections In Children Less Than Three Years Old , Time 5/28/2011 9:37:32 PM : كلية الطب
وصف الابستركت (Abstract)
المحتوى البكتيري لاخماج مجرى الدم في الاطفال دون سن الثالثة
الوصف الكامل (Full Abstract)
Bacterial Profile of Blood Stream Infections In Children Less Than Three Years Old
Alaa H. Al-Charrakh Ali M. Al-Muhana Zainab H. Al-Saadi
ABSTRACT
Despite considerable progress in hygiene, antimicrobial therapy, and supportive treatment, blood stream infections remain important causes of morbidity and mortality which, may reaches to 20%-30% in the United States. Microbiologic culturing of blood is the only available means for diagnosis of these infections and allows for successful recovery of bacteria in 99% in patients with bacteremia of septicemia. In this study, 247 blood specimens were collected from prematures, infants, and children (aged from 1 day to 3 years) admitted to the hospital of maternity and pediatrics in Najaf during the period from October to December 1996.
The following bacterial species were recovered: Klebsiella spp., E. coli, Staph aureus, Pseudomonas spp., Enterobacter spp. ?. hemolytic streptococci, St. pyogenes, St. pnenmoniae, Enterococcus. faecalis, viridans St., Alcaligens faecalis, acinetobacter calcoaceticus, Proteus spp., and Serratia marcescens. The most common etiologic agents of pediatric bacteremia were Klebsiella spp. and E. coli., together isolated from 68.4% of the blood samples studied.
The resistance of the recovered Klebsiella spp. isolates to a number of antimicrobial agents was determined. They were highly resistant to most of the antimicrobial agents studied. 59% to 83% of those isolates were resistant to pencillins (Amp, Amox), Cefotaxime (3rd generation cephalosporin), Gentamycin, Chloramphenicol and Trimethoprim-Sulfamethoxazole.Morderately 35-36% of Klebsiella spp. isolates were resistant to Cephalexin, Ceftizoxine, and Tetracycline, although these isolates highly sensitive to Rifampisin (97.2%). A pattern of multiresistance was observed which may explain the prevalence of these isolates in pediatric bacteremia in the area of the study.
Although Salmonella spp. are common in our country and considered (in other countries) as the most common causes of childhood septicaemia, which accounted for 15% of all, and 27% of community-acquired infections [10], Salmonella spp. was not recoded as etiologic agent of bacteremia in this study.
Key words: Pediatric bacteremia, Bacterial Profile, Klebsiella.
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