عنوان البحث(Papers / Research Title)
the immune status of patients with spyogenes tonsillites
الناشر \ المحرر \ الكاتب (Author / Editor / Publisher)
بهاء حمدي حكيم العميدي
Citation Information
بهاء,حمدي,حكيم,العميدي ,the immune status of patients with spyogenes tonsillites , Time 6/5/2011 6:20:52 PM : كلية طب الاسنان
وصف الابستركت (Abstract)
the immune status of patients with spyogenes tonsillites
الوصف الكامل (Full Abstract)
The Immune status of patients with S. pyogenes Tonsillitis
*Ibrahim,M.S. Shnawa **Baha, H.H.AL-Amiedi* Department of Biology , college of science and** Department of basic science , college of dentistry , university of BabylonCited at the fourth scientific conference –college of science-babylon university issue 2007
Abstract:
Twenty two clinically and culture proven (tonsillar swab culture ) bacterial tonsillitis were diagnosed as S. pyogenes tonsillitis patients. Blood with and without anticoagulant were collected from these patients. Serum total and globulin protein concentration, S. pyogenes specific antibody titres and leucoyte inhibitory factors (LIF) were performed.Systemic antibody responses were higher than mucosal antibody responses significant (16 cases) and non significant (6 cases). LIF were noted. Thus S. pyogenes epitopes stimulate both mucosal and systemic humoral and cellular responses during the tonsilar infections.Introduction:Tonsils (T) as lymph nodes are nodular aggregates of macrophages and lymphocytes that are layed down onto delicate reticular tissue and reticular cells (Parslow, 2001).Tonsils are considered as un capsulated lymphoid tissue associated with mucous membranes. Tonsils and the other organized lymphoid tissue of waldeyeris pharyngeal wring are inciuded with the nasal associated lymphoid tissue NALT such as adenoid (Bradtzeag , 1999,Parslow et al,2001).Food drink and exogenous and the endogenous potential pathogen can be drained by tonsils then finding their way to local lymphatics to the node matrix engulfed by marcrophages their antigens processed and presented to T lymphocyte which inturn activate B lymphocyte to grow proliferation and transfered to antibody synthesizing cells where by either insitive produce antibody or migrate into distant effector sites in the mucosal immune cornpartments. Systemic immune response may parall to this mucosal immune response specific to same pathogen(s) (Mims et al,2001,Parslow etal, 2001). In the present work tonsiler mucosal as
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