عنوان البحث(Papers / Research Title)
IL-1 BETA AND IL-6 CYTOKINES PROFILE IN OBESE AND OVER WEIGHT WOMEN IN
الناشر \ المحرر \ الكاتب (Author / Editor / Publisher)
اسراء عدنان ابراهيم البغدادي
Citation Information
اسراء,عدنان,ابراهيم,البغدادي ,IL-1 BETA AND IL-6 CYTOKINES PROFILE IN OBESE AND OVER WEIGHT WOMEN IN , Time 22/10/2017 07:14:29 : كلية العلوم للبنات
وصف الابستركت (Abstract)
IL-1 BETA AND IL-6 CYTOKINES PROFILE IN OBESE AND OVER WEIGHT WOMEN IN
الوصف الكامل (Full Abstract)
The occurrence of obesity has augmented fast through new year. Our previous study showed obesity was related with diseases and or infections recorded, adipose tissue mediates immune system. Present study aim is evaluation some immune aspect related with IL-1- Beta as pro-inflammatory cytokine and IL-6 cytokine as both pro and anti- inflammatory cytokine) production in obese versus normal weight women. Enzyme-linked immune sorbent assay (ELISA) used for detecting and quantifying cytokines. Results shows that the concentration of the IL-1Beta as pro inflammatory cytokine stood greater in obese and overweight women (186.2 ± 58.54, n=17) than in normal weight women (control group (20.41 ± 9.387, n=3), (F=220.4, P < 0.05) while here stayed not any substantial variances in IL-6 concentrations between test group (198.5 ± 34.93, n=15) in compare with control group (212.6 ± 122.9, n=3), (F=2.475, P=0.240). In conclusion, our result improved that obesity responsible in elevation level of pro- inflammatory cytokine IL-1 Beta and interleukin 6 play important role as both anti and proinflammatory cytokine. The occurrence of obesity has augmented fast through new year. Our previous study showed obesity was related with diseases and or infections recorded, adipose tissue mediates immune system. Present study aim is evaluation some immune aspect related with IL-1- Beta as pro-inflammatory cytokine and IL-6 cytokine as both pro and anti- inflammatory cytokine) production in obese versus normal weight women. Enzyme-linked immune sorbent assay (ELISA) used for detecting and quantifying cytokines. Results shows that the concentration of the IL-1Beta as pro inflammatory cytokine stood greater in obese and overweight women (186.2 ± 58.54, n=17) than in normal weight women (control group (20.41 ± 9.387, n=3), (F=220.4, P < 0.05) while here stayed not any substantial variances in IL-6 concentrations between test group (198.5 ± 34.93, n=15) in compare with control group (212.6 ± 122.9, n=3), (F=2.475, P=0.240). In conclusion, our result improved that obesity responsible in elevation level of pro- inflammatory cytokine IL-1 Beta and interleukin 6 play important role as both anti and proinflammatory cytokine.
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