Abstract
In Merjan teaching hospital we recorded (3200) cases of hand complaints in period from Nov.
2002 – June 2004. Of them, Dupuytren’s hand diseases were represented in (84) cases 2.6% the (study
group). which were investigated for the association and severity, with diabetes mellitus ,smoking and
other risk factors , this study group also were matched for age and gender with other three groups :
Group I: (230) Patients who had diabetes mellitus for more than (10) years duration, who were neither
smokers nor alcoholic or epileptics.
Group II: (300 ) community controls , who were smokers “ more than 20 cigarette per day for more
than 10 years “,who were neither diabetics nor alcoholic or epileptics .
Group III: ( 420 ) community controls , who were randomly selected .
The results showed that the Dupuytren’s disease is strongly associated with diabetes mellitus, where in
study group: 25% of Dupuytren’s were diabetics, while 11.9% of Dupuytren’s were smokers 2.3%
were epileptics on phenytoin.
Group I: 9.5% of diabetics patients had got Dupuytren’s
Group II :2.6% of smokers had got Dupuytren’s disease .
Group III: The total number of Dupuytren s disease were ( 7 ) cases 1.6 %. Grouped as follow ( 4 )
cases were diabetics , ( 1 ) case was smokers. And (2) cases had not apparent risk factors .
On basis of the results, the Dupuytren’s disease is strongly associated with diabetes mellitus, although
milder , appeared earlier in age than other risk factors and mostly bilateral.
There was no significant difference regarding incidence between different types of jobs , or
between dominant hands and non dominant ones .
The purpose of the present prospective case matched study , is to elucidate the role of diabetes
mellitus as main predisposing risk factor of Dupuytren’s disease In Babylon.