The addition of natural wastes to improve the mechanical properties of construction materials are becoming increasingly important over the past decades for economic and environmental advantages. The present study is an attempt in improving the mechanical and antibacterial surface properties of the cast stone by self compacting concrete method by using different volume fractions of palm leaf sheath fibers (PLSF) (0.1, 0.2 and 0.3) % and coated with nano Zno/Epoxy coating using doctor blade method , at different Zno ratios (0.5 ,1 and 1.5) %. The fresh concrete tests such as : slump flow test, V-funnel test and L-box test, were done . Also , the CS were characterized by tests of compressive strength, flexural strength and splitting tensile strength. The coatings were evaluated by antibacterial activity, Atomic force microscope, roughness and wettability. The results could prove the success of addition of 0.1 % PF in improving the compressive strength at (7, 14 and 28 days), flexural strength and splitting tensile strength at (28 days) of cast stone from 58 MPa, 11.06 MPa and 5.21 MPa to 65.3 MPa, 15.2 MPa and 5.35 MPa, respectively. In addition, increasing the PF content above 0.1 % showed undesirable compressive strength and flexural strength but improved splitting tensile strength for cast stone. Results of coating show that better concentration to killing bacterial E. coli is 1% Zno, where this concentration increase inhibition zone 19.5 mm and contact angles increased with Zno ratio increasing, therefore, resulting in less wettability