Bioactive glass-ceramics used as a replacement material for bone tissues because
of its bioactivity, compatibility, and abilities to form a crystallized hydroxyapatite
(HA) bonding layer which has a similarity in composition and structure to the
inorganic component of bones mineral phase. The major objectives of this research is
estimating the effects of using MgO as an additive on the property of bioactive glass
ceramic in 45SiO2, 24.5 Na2O, 6 P2O5, (24.5-x)CaO, X MgO where X= 0,1,3 and 5
wt.%. Bioactive glass ceramic was made by traditional glasses melting techniques at
1200°C for 2hr. Compressed sample sintered at (850)°C, the X-ray diffraction test
confirmed the formations of (Na2CaSi3O8) and (Na2Ca2Si3O9) phases in the
structure of pure bioglass-ceramic and with (1wt.%) MgO, while (Na2CaSiO4) and
CaMg(SiO3)2 phases were present in the structure of bioglass-ceramic with
(3wt.%)MgO, and CaMg(SiO3)2 phase in the structure of bioglass-ceramic with
(5wt.%) MgO. Results of mechanical and physical studies showed that increasing
(MgO wt.%) in glass structure led to improving the bending strength, compressive
strength, microhardness, and density associating with decreasing in porosity. FTIR
confirmed the formations of the Si-O-Mg bond. The biological test was done by
immersion the sample in (SBF) simulated body fluid for (21 days). XRD, SEM and pH
tests revealed that appetite layers made on the samples surface, giving an evidence of
their bioactivity. As general the results of the present study demonstrate that partial
replacements of CaO by MgO in 45S5 glass ceramic improve the mechanical
properties without altering the bioactivity suggesting that glass ceramic was suitable
for the biomedical applications